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Peptide record

TPDB11300

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11300
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLWDSIKNFGKTIALNVMDKIKCKIGGGCPP
Physicochemical Analysis
C148H243N39O40S3
REQHY
GK
3304.97
9.65
5
2
11
+3
3.32
0.006
88.06
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
170.20
6
Residue Composition
number
1
A
0
R
2
N
2
D
2
C
0
E
0
Q
5
G
0
H
4
I
2
L
5
K
1
M
1
F
2
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 4 L: 2 K: 5 M: 1 F: 1 P: 2 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
31
C148H243N39O40S3
3304.97
9.65
+3
3.32
0.006
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
50% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis. | Zoolog Sci | 2011
Evidence 2 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.