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Peptide record

TPDB11291

Antibacterial Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11291
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
FKFGSFIKRMWRSKLAKKLRAKGKELLRDYA
Physicochemical Analysis
C176H287N51O39S1
NCQHPTV
K
3773.59
11.60
11
2
14
+9
4.23
-0.694
72.58
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
185.23
3
Residue Composition
number
3
A
4
R
0
N
1
D
0
C
1
E
0
Q
2
G
0
H
1
I
4
L
7
K
1
M
3
F
0
P
2
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 4 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 7 M: 1 F: 3 P: 0 S: 2 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
31
C176H287N51O39S1
3773.59
11.60
+9
4.23
-0.694
Evidence Records 4 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
3.125 µM
Hemolytic Cytotoxic
10% Hemolysis | 3.125 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 2 Activity

Activity

65% Hemolysis
Toxicity
6.25 µM
Hemolytic Cytotoxic
65% Hemolysis | 6.25 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 3 Activity

Activity

100% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
100% Hemolysis | 12.5 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis