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Peptide record

TPDB11290

Antibacterial Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11290
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
EKALEKLIAIQKAIKGMLNGWFTGVGFRRKR
Physicochemical Analysis
C163H272N48O39S1
DCHPSY
K
3560.31
11.58
8
2
14
+6
5.21
-0.265
94.52
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
5500
154.48
3
Residue Composition
number
3
A
3
R
1
N
0
D
0
C
2
E
1
Q
4
G
0
H
3
I
3
L
5
K
1
M
2
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 3 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 4 H: 0 I: 3 L: 3 K: 5 M: 1 F: 2 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
31
C163H272N48O39S1
3560.31
11.58
+6
5.21
-0.265
Evidence Records 2 records
Evidence 1 Activity

Activity

61% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
61% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2. | Sci Rep | 2017
Evidence 2 Activity

Activity

80% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
80% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2. | Sci Rep | 2017