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Peptide record

TPDB11280

Antibacterial Anticancer Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11280
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RGVAKFASKGLGKDLAKLGVDLVACKISKQC
Physicochemical Analysis
C141H247N41O39S2
NEHMPTWY
K
3204.88
10.27
7
2
13
+5
5.46
0.184
103.87
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
3.90
5
Residue Composition
number
4
A
1
R
0
N
2
D
2
C
0
E
1
Q
4
G
0
H
1
I
4
L
6
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 2 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 1 L: 4 K: 6 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
31
C141H247N41O39S2
3204.88
10.27
+5
5.46
0.184
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells. | Peptides | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis>200 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2013 Jan 39:95-102.