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Peptide record

TPDB11273

Antibacterial Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB11273
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
LVQRGRFGRFLRKIRRFRPKVTITIQGSARF
Physicochemical Analysis
C171H287N59O37
NDCEHMWY
R
3761.53
13.25
10
0
12
+10
3.91
-0.429
84.84
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
1
A
8
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
3
I
2
L
2
K
0
M
4
F
1
P
1
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 2 K: 2 M: 0 F: 4 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
31
C171H287N59O37
3761.53
13.25
+10
3.91
-0.429
Evidence Records 4 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
100% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The central kink region of fowlicidin-2, an alpha-helical host defense peptide, is critically involved in bacterial killing and endotoxin neutralization. | J Innate Immun | 2009
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
90% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The central kink region of fowlicidin-2, an alpha-helical host defense peptide, is critically involved in bacterial killing and endotoxin neutralization. | J Innate Immun | 2009
Evidence 3 Activity

Activity

45% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
45% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The central kink region of fowlicidin-2, an alpha-helical host defense peptide, is critically involved in bacterial killing and endotoxin neutralization. | J Innate Immun | 2009
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis