Back to search

Peptide record

TPDB11266

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11266
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
ALWKTMLKKLGTVALHAGKAALGAVADTISQ
Physicochemical Analysis
C143H243N39O39S1
RNCEFPY
A
3164.80
10.55
5
1
17
+3
1.07
0.503
116.77
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
173.79
5
Residue Composition
number
7
A
0
R
0
N
1
D
0
C
0
E
1
Q
3
G
1
H
1
I
5
L
4
K
1
M
0
F
0
P
1
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 5 K: 4 M: 1 F: 0 P: 0 S: 1 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
31
C143H243N39O39S1
3164.80
10.55
+3
1.07
0.503
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
10 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
10 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
10 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
100 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 10 uM), E. coli (MIC 10 uM) and C. albicans (MIC 100 uM).
Evidence 7 Activity

Activity

<20% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
<20% Hemolysis | 10 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Novel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling. | J Cell Mol Med | 2018
Evidence 8 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Cell Mol Med. 2019 Feb 23(2):1300-1312.
Evidence 9 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.