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Peptide record

TPDB11249

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11249
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GAFGNFLKGVAKKAGLKILSIAQCKLFGTC
Physicochemical Analysis
C142H235N37O35S2
RDEHMPWY
GK
3084.77
10.39
5
0
14
+5
-1.07
0.633
101.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.05
6
Residue Composition
number
4
A
0
R
1
N
0
D
2
C
0
E
1
Q
5
G
0
H
2
I
4
L
5
K
0
M
3
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 5 H: 0 I: 2 L: 4 K: 5 M: 0 F: 3 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
30
C142H235N37O35S2
3084.77
10.39
+5
-1.07
0.633
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
21 %
[Ref.21171145] It has 21% hemolysis at 100 µg/ml against rabbit red blood cell

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
J Pept Sci. 2011 Jan 17(1):68-72.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

21% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
21% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two novel antimicrobial peptides from skin secretions of the frog, Rana nigrovittata. | J Pept Sci | 2011
Evidence 3 Activity

Activity

% Hemolysis
Toxicity
21 %
Hemolytic
Hemolytic_activity: [Ref.21171145] It has 21% hemolysis at 100 µg/ml against rabbit red blood cell

Target

erythrocytes

Source & Reference

NA
DRAMP
J Pept Sci. 2011 Jan 17(1):68-72.
Evidence 4 Hemolysis

Activity

21 %
% Hemolysis
[Ref.21171145] It has 21% hemolysis at 100 µg/ml against rabbit red blood cell
Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
J Pept Sci. 2011 Jan 17(1):68-72.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.