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Peptide record

TPDB11245

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11245
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ACYCRIPACFAGERRYGTCFYLGRVWAFCC
Physicochemical Analysis
C156H225N43O37S6
NDQHKMS
C
3487.13
8.30
4
1
14
+3
-5.10
0.443
49.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
10345
296.66
10
Residue Composition
number
4
A
4
R
0
N
0
D
6
C
1
E
0
Q
3
G
0
H
1
I
1
L
0
K
0
M
3
F
1
P
0
S
1
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 0 M: 0 F: 3 P: 1 S: 0 T: 1 W: 1 Y: 3 V: 1
Chemical Descriptors
30
C156H225N43O37S6
3487.13
8.30
+3
-5.10
0.443
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.4 µM

Target

Escherichia coli ML35p

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
In low salt conditions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus
Evidence 2 Activity

Activity

MIC
Antibacterial
2.2 µM

Target

L. monocytogenes EGD

Source & Reference

dbAMP DRAMP

Other

itions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albic
Evidence 3 Activity

Activity

MIC
Antibacterial
3.5 µM

Target

Staphylococcus aureus MRSA ATCC 33591

Source & Reference

dbAMP DRAMP

Other

C 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
3.9 µM

Target

Candida albicans 820

Source & Reference

dbAMP DRAMP

Other

2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
2.4 µM

Target

Escherichia coli ML35p

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
In low salt conditions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus
Evidence 6 Activity

Activity

MIC
Antifungal
2.2 µM

Target

L. monocytogenes EGD

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

itions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albic
Evidence 7 Activity

Activity

MIC
Antifungal
3.5 µM

Target

Staphylococcus aureus MRSA ATCC 33591

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
3.9 µM

Target

Candida albicans 820

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
2.4 µM

Target

Escherichia coli ML35p

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
In low salt conditions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus
Evidence 10 Activity

Activity

MIC
Antiparasitic
2.2 µM

Target

L. monocytogenes EGD

Source & Reference

DRAMP

Other

itions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albic
Evidence 11 Activity

Activity

MIC
Antiparasitic
3.5 µM

Target

Staphylococcus aureus MRSA ATCC 33591

Source & Reference

DRAMP

Other

C 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
3.9 µM

Target

Candida albicans 820

Source & Reference

DRAMP

Other

2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 13 Activity

Activity

MIC
Antiviral
2.4 µM

Target

Escherichia coli ML35p

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
In low salt conditions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus
Evidence 14 Activity

Activity

MIC
Antiviral
2.2 µM

Target

L. monocytogenes EGD

Source & Reference

DRAMP

Other

itions, active against the Gram- bacterium E. coli ML35p (MIC 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albic
Evidence 15 Activity

Activity

MIC
Antiviral
3.5 µM

Target

Staphylococcus aureus MRSA ATCC 33591

Source & Reference

DRAMP

Other

C 2.4 uM), the Gram+ bacteria L. monocytogenes EGD (MIC 2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).
Evidence 16 Activity

Activity

MIC
Antiviral
3.9 µM

Target

Candida albicans 820

Source & Reference

DRAMP

Other

2.2 uM) and methicillin-resistant S. aureus MRSA ATCC 33591 (MIC 3.5 uM), and the fungus C. albicans 820 (MIC 3.9 uM).