Back to search

Peptide record

TPDB11235

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11235
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GFFTLIKAANKLINKTVNKEAGKGGLEIMA
Physicochemical Analysis
C144H242N38O40S1
RDCQHPSWY
K
3177.80
10.38
5
2
14
+3
4.86
0.127
101.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
4
A
0
R
3
N
0
D
0
C
2
E
0
Q
4
G
0
H
3
I
3
L
5
K
1
M
2
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 0 C: 0 E: 2 Q: 0 G: 4 H: 0 I: 3 L: 3 K: 5 M: 1 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
30
C144H242N38O40S1
3177.80
10.38
+3
4.86
0.127
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 2 Activity

Activity

(13.3±4.8)% degranulation
Toxicity
50 µg/mL
Cytotoxic
(13.3±4.8)% degranulation | 50 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:17272268]Non-hemolytic activity against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Cell Proteomics. 2007 May 6(5):882-894.