Peptide record

TPDB11230

Lf-CATH1 Antibacterial Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11230
Lf-CATH1
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0 DBAASP
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
PPCRGIFCRRVGSSSAIARPGKTLSTFITV
Physicochemical Analysis
C139H233N43O38S2
NDEQHMWY
RS
3178.76
11.95
5
0
10
+5
2.12
0.223
78.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
125
3.93
9
Residue Composition
number
2
A
4
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
3
I
1
L
1
K
0
M
2
F
3
P
4
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 3 L: 1 K: 1 M: 0 F: 2 P: 3 S: 4 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
30
C139H233N43O38S2
3178.76
11.95
+5
2.12
0.223
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis). | FEBS J | 2013
Evidence 2 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP