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Peptide record

TPDB11229

Antibacterial Antifungal standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11229
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 30-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GSAIRCGESCLLGKCYTPGCTCDRPICKKN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C129H218N40O41S6
QHMFWV
C
3177.75
8.31
5
2
6
+3
1.59
-0.230
55.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
0.59
12
Residue Composition
number
1
A
2
R
1
N
1
D
6
C
1
E
0
Q
4
G
0
H
2
I
2
L
3
K
0
M
0
F
2
P
2
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 2 L: 2 K: 3 M: 0 F: 0 P: 2 S: 2 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
30 reviewed residue count
C129H218N40O41S6 sequence-only estimate (linear, free termini)
3177.75 sequence-only estimate (linear, free termini)
8.31 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.59 sequence-only estimate (linear, free termini)
-0.230 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 0.5 uM). Updated 7/2021
Evidence 2 Activity

Activity

MIC
Antifungal
0.5 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against E. coli (MIC 0.5 uM). Updated 7/2021