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Peptide record

TPDB11228

Antibacterial Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11228
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLLLDTVKGAAKNVAGILLNKLKCKMTGDC
Physicochemical Analysis
C134H239N37O39S3
REQHFPSWY
L
3088.78
9.65
5
2
13
+3
3.82
0.383
120.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.05
6
Residue Composition
number
3
A
0
R
2
N
2
D
2
C
0
E
0
Q
4
G
0
H
1
I
6
L
5
K
1
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 6 K: 5 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
30
C134H239N37O39S3
3088.78
9.65
+3
3.82
0.383
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after
Evidence 2 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

S.aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after incubation with 50% serum (
Evidence 3 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

C.albicans

Source & Reference

dbAMP

Other

Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after incubation with 50% serum (serum-sensitive). Updated 7/2020.
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after
Evidence 5 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

S.aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after incubation with 50% serum (
Evidence 6 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

C.albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 12.5 ug/ml), S.aureus (MIC >200 ug/ml), and C.albicans (MIC >200 ug/ml). Activity reduced/lost after incubation with 50% serum (serum-sensitive). Updated 7/2020.
Evidence 7 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Different expression profiles of bioactive peptides in Pelophylax nigromaculatus from distinct regions. | Biosci Biotechnol Biochem | 2013