Back to search

Peptide record

TPDB11227

Lf-CATH2 Antibacterial Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11227
Lf-CATH2
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0 DBAASP
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GKCNVLCQLKQKLRSIGSGSHIGSVVLPRG
Physicochemical Analysis
C134H236N44O38S2
ADEMFTWY
G
3135.74
10.82
6
0
9
+5
5.02
0.020
107.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.99
9
Residue Composition
number
0
A
2
R
1
N
0
D
2
C
0
E
2
Q
5
G
1
H
2
I
4
L
3
K
0
M
0
F
1
P
4
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 2 G: 5 H: 1 I: 2 L: 4 K: 3 M: 0 F: 0 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
30
C134H236N44O38S2
3135.74
10.82
+5
5.02
0.020
Evidence Records 2 records
Evidence 1 Activity

Activity

14% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
14% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and polymorphism discovery of the cathelicidins, Lf-CATHs in ranid amphibian (Limnonectes fragilis). | FEBS J | 2013
Evidence 2 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP