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Peptide record

TPDB11213

Antibacterial Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11213
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GILMDTFKGAAKNVAGFLLDKLKCKISGGC
Physicochemical Analysis
C138H232N36O38S3
REQHPWY
GK
3099.76
9.65
5
2
13
+3
1.88
0.427
97.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.03
5
Residue Composition
number
3
A
0
R
1
N
2
D
2
C
0
E
0
Q
5
G
0
H
2
I
4
L
5
K
1
M
2
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 4 K: 5 M: 1 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
30
C138H232N36O38S3
3099.76
9.65
+3
1.88
0.427
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.4 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S.aureus ATCC 25923 (inactive), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 9.4 uM), P.aeruginosa CGMCC 1.50, K.pneumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM
Evidence 2 Activity

Activity

MIC
Antibacterial
75 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

steroides 201118 (MIC 9.4 uM), P.aeruginosa CGMCC 1.50, K.pneumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM), C.albicans ATCC 10231, and C.glabrata 090902 (MIC 150 uM). Updated 5/2019 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
150 µM

Target

C.glabrata 090902

Source & Reference

dbAMP

Other

neumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM), C.albicans ATCC 10231, and C.glabrata 090902 (MIC 150 uM). Updated 5/2019 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
9.4 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S.aureus ATCC 25923 (inactive), E.faecalis 981 (inactive), N. asteroides 201118 (MIC 9.4 uM), P.aeruginosa CGMCC 1.50, K.pneumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM
Evidence 5 Activity

Activity

MIC
Antifungal
75 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

steroides 201118 (MIC 9.4 uM), P.aeruginosa CGMCC 1.50, K.pneumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM), C.albicans ATCC 10231, and C.glabrata 090902 (MIC 150 uM). Updated 5/2019 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
150 µM

Target

C.glabrata 090902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

neumoniae 08040724 (inactive), E. coli ATCC 25922 (MIC 75 uM), C.albicans ATCC 10231, and C.glabrata 090902 (MIC 150 uM). Updated 5/2019 7/2021
Evidence 7 Activity

Activity

40.9% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
40.9% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 8 Activity

Activity

23.1% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
23.1% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 9 Activity

Activity

11.7% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
11.7% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 10 Activity

Activity

0% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
0% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017