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Peptide record

TPDB11197

Antibacterial Anticancer Antifungal Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB11197
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GIKHILFMAKTKLPRATCTAEIKENCDRKK
Physicochemical Analysis
C150H259N45O41S3
QSWYV
K
3445.16
10.27
9
3
10
+5
10.69
-0.583
75.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.63
6
Residue Composition
number
3
A
2
R
1
N
1
D
2
C
2
E
0
Q
1
G
1
H
3
I
2
L
6
K
1
M
1
F
1
P
0
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 1 C: 2 E: 2 Q: 0 G: 1 H: 1 I: 3 L: 2 K: 6 M: 1 F: 1 P: 1 S: 0 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
30
C150H259N45O41S3
3445.16
10.27
+5
10.69
-0.583
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1-500 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 1-500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:5% Hemolysis=1-500µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Oct 11 6:35019.