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Peptide record

TPDB11162

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11162
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFMDTAKNAAKNVAVTLLDNLKCKITKAC
Physicochemical Analysis
C133H229N37O40S3
REQHPSWY
AK
3082.69
9.65
5
2
13
+3
4.56
0.121
91.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.05
8
Residue Composition
number
5
A
0
R
3
N
2
D
2
C
0
E
0
Q
1
G
0
H
1
I
3
L
5
K
1
M
1
F
0
P
0
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 5 M: 1 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
29
C133H229N37O40S3
3082.69
9.65
+3
4.56
0.121
Evidence Records 5 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
3.5 %
[Ref.17272268] RCH=15.4 ± 3.5% against rabbit red blood cells at 50 µg/ml. RCH, red cell hemolysis.

Target

rabbit red blood cells

Source & Reference

Hemolytik PD_Hemolysis
DRAMP4
Mol Cell Proteomics. 2007 May 6(5):882-894.

Other

Source Activity Label Source Definition
Hemolysis
Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

15% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
15% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 3 Activity

Activity

(7.7±2.6)% degranulation
Toxicity
50 µg/mL
Cytotoxic
(7.7±2.6)% degranulation | 50 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 4 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.17272268] RCH=15.4 ± 3.5% against rabbit red blood cells at 50 µg/ml. RCH, red cell hemolysis.

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Cell Proteomics. 2007 May 6(5):882-894.
Evidence 5 Hemolysis

Activity

3.5 %
% Hemolysis
[Ref.17272268] RCH=15.4 ± 3.5% against rabbit red blood cells at 50 µg/ml. RCH, red cell hemolysis.
Hemolysis

Target

rabbit red blood cells

Source & Reference

HemoPI PD_Hemolysis
Mol Cell Proteomics. 2007 May 6(5):882-894.
DRAMP4
PD_Hemolysis