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Peptide record

TPDB11158

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11158
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LKIPGFVKDTLKKVAKGIFSAVAGAMTPS
Physicochemical Analysis
C138H232N34O36S1
RNCEQHWY
K
2975.63
10.71
5
1
14
+4
2.95
0.466
97.59
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
4
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
2
I
2
L
5
K
1
M
2
F
2
P
2
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 5 M: 1 F: 2 P: 2 S: 2 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
29
C138H232N34O36S1
2975.63
10.71
+4
2.95
0.466
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
20-40 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 3 Activity

Activity

MIC
Antiparasitic
20-40 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 4 Activity

Activity

MIC
Antiviral
20-40 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
>300 µM
Hemolytic Cytotoxic
50% Hemolysis | >300 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The hymenochirins: a family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae). | Peptides | 2012
Evidence 6 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.