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Peptide record

TPDB11139

Antibacterial Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11139
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIGSMLLGLAKNVGMSLLNKAQCKISGKC
Physicochemical Analysis
C125H224N36O36S4
RDEHFPTWY
GL
2935.61
10.17
4
0
12
+4
1.19
0.486
111.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.26
8
Residue Composition
number
2
A
0
R
2
N
0
D
2
C
0
E
1
Q
5
G
0
H
2
I
5
L
4
K
2
M
0
F
0
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 2 E: 0 Q: 1 G: 5 H: 0 I: 2 L: 5 K: 4 M: 2 F: 0 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
29
C125H224N36O36S4
2935.61
10.17
+4
1.19
0.486
Evidence Records 5 records
Evidence 1 Activity

Activity

49.7% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
49.7% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Three novel antimicrobial peptides from the skin of the Indian bronzed frog Hylarana temporalis (Anura: Ranidae). | J Pept Sci | 2011
Evidence 2 Activity

Activity

87.2% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
87.2% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Three novel antimicrobial peptides from the skin of the Indian bronzed frog Hylarana temporalis (Anura: Ranidae). | J Pept Sci | 2011
Evidence 3 Activity

Activity

92.5% Hemolysis
Toxicity
150 µg/mL
Hemolytic Cytotoxic
92.5% Hemolysis | 150 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Three novel antimicrobial peptides from the skin of the Indian bronzed frog Hylarana temporalis (Anura: Ranidae). | J Pept Sci | 2011
Evidence 4 Activity

Activity

100% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Three novel antimicrobial peptides from the skin of the Indian bronzed frog Hylarana temporalis (Anura: Ranidae). | J Pept Sci | 2011
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis