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Peptide record

TPDB11131

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11131
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFMDTAKNVAKNVAVTLLDKLKCKITGGC
Physicochemical Analysis
C132H228N36O39S3
REQHPSWY
K
3039.66
9.65
5
2
12
+3
4.57
0.234
94.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.11
7
Residue Composition
number
3
A
0
R
2
N
2
D
2
C
0
E
0
Q
3
G
0
H
1
I
3
L
5
K
1
M
1
F
0
P
0
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 5 M: 1 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
29
C132H228N36O39S3
3039.66
9.65
+3
4.57
0.234
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/202
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 4 Activity

Activity

MIC
Antibacterial
100 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

oli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 5 Activity

Activity

MIC
Antifungal
100 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC
Evidence 6 Activity

Activity

MIC
Antifungal
25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/202
Evidence 7 Activity

Activity

MIC
Antifungal
12.5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 8 Activity

Activity

MIC
Antifungal
100 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

oli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 9 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC
Evidence 10 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/202
Evidence 11 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 12 Activity

Activity

MIC
Antiparasitic
100 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

oli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 13 Activity

Activity

MIC
Antiviral
100 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC
Evidence 14 Activity

Activity

MIC
Antiviral
25 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/202
Evidence 15 Activity

Activity

MIC
Antiviral
12.5 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Active against E. coli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023
Evidence 16 Activity

Activity

MIC
Antiviral
100 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

oli (MIC 100 uM), S. aureus (MIC 25 uM), MRSA (MIC 100 uM), B. subtilis (MIC 12.5 uM) and C. albicans (MIC 100 uM). Updated 6/2023