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Peptide record

TPDB11130

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11130
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
GFMDTAKNVAKNVAVTLIDNLKCKITKAC
Physicochemical Analysis
C135H233N37O40S3
REQHPSWY
K
3110.74
9.65
5
2
13
+3
5.05
0.228
97.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.02
8
Residue Composition
number
4
A
0
R
3
N
2
D
2
C
0
E
0
Q
1
G
0
H
2
I
2
L
5
K
1
M
1
F
0
P
0
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 5 M: 1 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
29
C135H233N37O40S3
3110.74
9.65
+3
5.05
0.228
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
2.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In
Evidence 3 Activity

Activity

MIC
Antibacterial
8.4 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemoly
Evidence 4 Activity

Activity

MIC
Antibacterial
1.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

inst E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemolysis at 50 ug/ml.
Evidence 5 Activity

Activity

MIC
Antifungal
4.2 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In
Evidence 7 Activity

Activity

MIC
Antifungal
8.4 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemoly
Evidence 8 Activity

Activity

MIC
Antifungal
1.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

inst E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemolysis at 50 ug/ml.
Evidence 9 Activity

Activity

MIC
Antiparasitic
4.2 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiparasitic
2.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In
Evidence 11 Activity

Activity

MIC
Antiparasitic
8.4 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemoly
Evidence 12 Activity

Activity

MIC
Antiparasitic
1.1 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

inst E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemolysis at 50 ug/ml.
Evidence 13 Activity

Activity

MIC
Antiviral
4.2 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml).
Evidence 14 Activity

Activity

MIC
Antiviral
2.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In
Evidence 15 Activity

Activity

MIC
Antiviral
8.4 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemoly
Evidence 16 Activity

Activity

MIC
Antiviral
1.1 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

inst E. coli (MIC 4.2 ug/ml), S. aureus (MIC 2.1 ug/ml), B. subtilis (MIC 8.4 ug/ml), and C. albicans (MIC 1.1 ug/ml). Aslo histamine release. In vitro Toxicity: 15.4% hemolysis at 50 ug/ml.
Evidence 17 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.