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Peptide record

TPDB11127

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11127
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFMDTAKNVAKNMAVTLLDNLKCKITKAC
Physicochemical Analysis
C135H233N37O40S4
REQHPSWY
K
3142.80
9.65
5
2
13
+3
4.50
0.124
87.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.98
8
Residue Composition
number
4
A
0
R
3
N
2
D
2
C
0
E
0
Q
1
G
0
H
1
I
3
L
5
K
2
M
1
F
0
P
0
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 2 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 5 M: 2 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
29
C135H233N37O40S4
3142.80
9.65
+3
4.50
0.124
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
3.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
3.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
7.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
3.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
3.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
7.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
3.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
3.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
7.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
3.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 7.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
3.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 7.5 ug/ml), Gram+ bacteria S. aureus (MIC 3.8 ug/ml), and yeast C. albicans (MIC 3.8 ug/ml). Updated 7/2021