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Peptide record

TPDB11124

Cathelicidin CATH3 Cc-CATH3 Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11124
Cathelicidin CATH3 Cc-CATH3
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0 DBAASP
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
RVRRFWPLVPVAINTVAAGINLYKAIRRK
Physicochemical Analysis
C157H261N49O34
DCEQHMS
R
3379.11
12.58
7
0
16
+7
1.55
0.141
121.03
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6990
206.86
4
Residue Composition
number
4
A
5
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
2
K
0
M
1
F
2
P
0
S
1
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 4 R: 5 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 2 M: 0 F: 1 P: 2 S: 0 T: 1 W: 1 Y: 1 V: 4
Chemical Descriptors
29
C157H261N49O34
3379.11
12.58
+7
1.55
0.141
Evidence Records 55 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.2 µM

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 0.2 uM), clinical strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401
Evidence 2 Activity

Activity

MIC
Antibacterial
0.7 µM

Target

N. asteroids

Source & Reference

dbAMP

Other

l strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxyt
Evidence 3 Activity

Activity

MIC
Antibacterial
5.6 µM

Target

Enterococcus faecalis IS981

Source & Reference

dbAMP

Other

S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A.
Evidence 4 Activity

Activity

MIC
Antibacterial
1.4 µM

Target

P. acnes

Source & Reference

dbAMP

Other

01 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A.
Evidence 5 Activity

Activity

MIC
Antibacterial
22.2 µM

Target

Klebsiella oxytoca

Source & Reference

dbAMP

Other

0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM),
Evidence 6 Activity

Activity

MIC
Antibacterial
1.4 µM

Target

A. baumannii IS 2178 or Drb

Source & Reference

dbAMP

Other

M), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATC
Evidence 7 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

A. baumannii IS 2373

Source & Reference

dbAMP

Other

uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.
Evidence 8 Activity

Activity

MIC
Antibacterial
2.8-11.1 µM

Target

Escherichia coli IS strains

Source & Reference

dbAMP

Other

1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.coli ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >
Evidence 9 Activity

Activity

MIC
Antibacterial
22.2 µM

Target

Klebsiella pneumoniae IS1400

Source & Reference

dbAMP

Other

ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. alb
Evidence 10 Activity

Activity

MIC
Antibacterial
1.4 µM

Target

P. mirabilis

Source & Reference

dbAMP

Other

niae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC
Evidence 11 Activity

Activity

MIC
Antibacterial
0.7 µM

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP

Other

.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 12 Activity

Activity

MIC
Antibacterial
5.6 µM

Target

C. glabrata IS 0902

Source & Reference

dbAMP

Other

. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
0.2 µM

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ S. aureus ATCC 2592 (MIC 0.2 uM), clinical strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401
Evidence 14 Activity

Activity

MIC
Antifungal
0.7 µM

Target

N. asteroids

Source & Reference

dbAMP CAFPdb Antifungipept

Other

l strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxyt
Evidence 15 Activity

Activity

MIC
Antifungal
5.6 µM

Target

Enterococcus faecalis IS981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A.
Evidence 16 Activity

Activity

MIC
Antifungal
1.4 µM

Target

P. acnes

Source & Reference

dbAMP CAFPdb Antifungipept

Other

01 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A.
Evidence 17 Activity

Activity

MIC
Antifungal
22.2 µM

Target

Klebsiella oxytoca

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM),
Evidence 18 Activity

Activity

MIC
Antifungal
1.4 µM

Target

A. baumannii IS 2178 or Drb

Source & Reference

dbAMP CAFPdb Antifungipept

Other

M), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATC
Evidence 19 Activity

Activity

MIC
Antifungal
2.5 µM

Target

A. baumannii IS 2373

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.
Evidence 20 Activity

Activity

MIC
Antifungal
2.8-11.1 µM

Target

Escherichia coli IS strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.coli ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >
Evidence 21 Activity

Activity

MIC
Antifungal
22.2 µM

Target

Klebsiella pneumoniae IS1400

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. alb
Evidence 22 Activity

Activity

MIC
Antifungal
1.4 µM

Target

P. mirabilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

niae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC
Evidence 23 Activity

Activity

MIC
Antifungal
0.7 µM

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 24 Activity

Activity

MIC
Antifungal
5.6 µM

Target

C. glabrata IS 0902

Source & Reference

dbAMP CAFPdb Antifungipept

Other

. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 25 Activity

Activity

MIC
Antiparasitic
0.2 µM

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 0.2 uM), clinical strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401
Evidence 26 Activity

Activity

MIC
Antiparasitic
0.7 µM

Target

N. asteroids

Source & Reference

NA

Other

l strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxyt
Evidence 27 Activity

Activity

MIC
Antiparasitic
5.6 µM

Target

Enterococcus faecalis IS981

Source & Reference

NA

Other

S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A.
Evidence 28 Activity

Activity

MIC
Antiparasitic
1.4 µM

Target

P. acnes

Source & Reference

NA

Other

01 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A.
Evidence 29 Activity

Activity

MIC
Antiparasitic
22.2 µM

Target

Klebsiella oxytoca

Source & Reference

NA

Other

0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM),
Evidence 30 Activity

Activity

MIC
Antiparasitic
1.4 µM

Target

A. baumannii IS 2178 or Drb

Source & Reference

NA

Other

M), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATC
Evidence 31 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

A. baumannii IS 2373

Source & Reference

NA

Other

uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.
Evidence 32 Activity

Activity

MIC
Antiparasitic
2.8-11.1 µM

Target

Escherichia coli IS strains

Source & Reference

NA

Other

1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.coli ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >
Evidence 33 Activity

Activity

MIC
Antiparasitic
22.2 µM

Target

Klebsiella pneumoniae IS1400

Source & Reference

NA

Other

ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. alb
Evidence 34 Activity

Activity

MIC
Antiparasitic
1.4 µM

Target

P. mirabilis

Source & Reference

NA

Other

niae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC
Evidence 35 Activity

Activity

MIC
Antiparasitic
0.7 µM

Target

Candida albicans ATCC 2002

Source & Reference

NA

Other

.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 36 Activity

Activity

MIC
Antiparasitic
5.6 µM

Target

C. glabrata IS 0902

Source & Reference

NA

Other

. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 37 Activity

Activity

MIC
Antiviral
0.2 µM

Target

Staphylococcus aureus ATCC 2592

Source & Reference

NA

Other

Active against Gram+ S. aureus ATCC 2592 (MIC 0.2 uM), clinical strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401
Evidence 38 Activity

Activity

MIC
Antiviral
0.7 µM

Target

N. asteroids

Source & Reference

NA

Other

l strains (MIC 0.7-2.8 uM), S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxyt
Evidence 39 Activity

Activity

MIC
Antiviral
5.6 µM

Target

Enterococcus faecalis IS981

Source & Reference

NA

Other

S.epidermidis (Not detected), S. haemolyticus IS 2401 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A.
Evidence 40 Activity

Activity

MIC
Antiviral
1.4 µM

Target

P. acnes

Source & Reference

NA

Other

01 or DRa, N. asteroids (MIC 0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A.
Evidence 41 Activity

Activity

MIC
Antiviral
22.2 µM

Target

Klebsiella oxytoca

Source & Reference

NA

Other

0.7 uM), E. faecalis IS981 (MIC 5.6 uM), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM),
Evidence 42 Activity

Activity

MIC
Antiviral
1.4 µM

Target

A. baumannii IS 2178 or Drb

Source & Reference

NA

Other

M), E. faecium IS 1299, P. acnes (MIC 1.4 uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATC
Evidence 43 Activity

Activity

MIC
Antiviral
2.5 µM

Target

A. baumannii IS 2373

Source & Reference

NA

Other

uM), Gram- K. oxytoca (MIC 22.2 uM), A. sobria, A. baumannii IS 2178 or Drb (MIC 1.4 uM), A. baumannii IS 2373 (MIC 2.5 uM), S. maltophilia (MIC 1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.
Evidence 44 Activity

Activity

MIC
Antiviral
2.8-11.1 µM

Target

Escherichia coli IS strains

Source & Reference

NA

Other

1.4 or 5.6 uM), P. aeruginosa ATCC 27853, IS 1411-3 (MIC 5.6 uM), E.coli ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >
Evidence 45 Activity

Activity

MIC
Antiviral
22.2 µM

Target

Klebsiella pneumoniae IS1400

Source & Reference

NA

Other

ATCC 27853 (ND), E. coli IS strains (MIC 2.8-11.1 uM), K.pneumoniae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. alb
Evidence 46 Activity

Activity

MIC
Antiviral
1.4 µM

Target

P. mirabilis

Source & Reference

NA

Other

niae IS strains (ND), ONLY K. pneumoniae IS1400 (MIC 22.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC
Evidence 47 Activity

Activity

MIC
Antiviral
0.7 µM

Target

Candida albicans ATCC 2002

Source & Reference

NA

Other

.2 uM), P-vulgaris (MIC >29.6 uM), P. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 48 Activity

Activity

MIC
Antiviral
5.6 µM

Target

C. glabrata IS 0902

Source & Reference

NA

Other

. mirabilis (MIC 1.4 uM), S.typhi IS 1408 (ND), fungi C. albicans ATCC 2002 (MIC 0.7 uM), C. glabrata IS 0902 (MIC 5.6 uM), and slime mold (MIC 0.7 uM).
Evidence 49 Activity

Activity

0% Hemolysis
Toxicity
20 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 20 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011
Evidence 50 Activity

Activity

1% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011
Evidence 51 Activity

Activity

IC50
Toxicity
58 µg/mL
Cytotoxic
IC50 | 58 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Gene cloning, expression and characterization of avian cathelicidin orthologs, Cc-CATHs, from Coturnix coturnix. | FEBS J | 2011
Evidence 52 Activity

Activity

9% Cytotoxicity
Toxicity
64 µg/mL
Cytotoxic
9% Cytotoxicity | 64 | µg/mL | target cell: Pig kidney epithelial cells PK15

Target

Pig kidney epithelial cells PK15

Source & Reference

NA
DBAASP
Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens | Vet Res | 2024
Evidence 53 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens | Vet Res | 2024
Evidence 54 Activity

Activity

2.3% Hemolysis
Toxicity
160 µg/mL
Hemolytic Cytotoxic
2.3% Hemolysis | 160 | µg/mL | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens | Vet Res | 2024
Evidence 55 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP