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Peptide record

TPDB11121

Antibacterial Antifungal Antiparasitic standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11121
Antibacterial Antifungal Antiparasitic
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP i2APP
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antifungal, and Antiparasitic) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
RRIPRPILLPWRPPRPIPRPQPQPIPRWL
Physicochemical Analysis
C171H276N54O32
ANDCEGHKMFSTYV
P
3600.42
13.18
7
0
9
+7
5.16
-0.983
94.14
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
305.52
2
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
4
I
3
L
0
K
0
M
0
F
11
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 4 L: 3 K: 0 M: 0 F: 0 P: 11 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
29
C171H276N54O32
3600.42
13.18
+7
5.16
-0.983
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

S. enterica serovar Typhimurium 14028s

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
ctive against Gram- E. coli O157:H7, 0111, or UB1005 rough K-12 strain (MIC 8-32 ug/ml), S. enterica serovar Typhimurium 14028s (MIC 32 ug/ml), S. enterica serovar Typhimurium MS4252S (phoPQ mutant defensin supersusceptible) (MIC 2
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Staphylococcus epidermidis clinical isolate

Source & Reference

dbAMP

Other

t (MIC 16-32 ug/ml), Gram+ S. aureus NCTC 4163 or MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/m
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP

Other

r MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/ml or greater) ( PubMed ).
Evidence 4 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

S. enterica serovar Typhimurium 14028s

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
ctive against Gram- E. coli O157:H7, 0111, or UB1005 rough K-12 strain (MIC 8-32 ug/ml), S. enterica serovar Typhimurium 14028s (MIC 32 ug/ml), S. enterica serovar Typhimurium MS4252S (phoPQ mutant defensin supersusceptible) (MIC 2
Evidence 5 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Staphylococcus epidermidis clinical isolate

Source & Reference

dbAMP CAFPdb Antifungipept

Other

t (MIC 16-32 ug/ml), Gram+ S. aureus NCTC 4163 or MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/m
Evidence 6 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

r MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/ml or greater) ( PubMed ).
Evidence 7 Activity

Activity

MIC
Antiparasitic
32 µg/mL

Target

S. enterica serovar Typhimurium 14028s

Source & Reference

NA

Other

ctive against Gram- E. coli O157:H7, 0111, or UB1005 rough K-12 strain (MIC 8-32 ug/ml), S. enterica serovar Typhimurium 14028s (MIC 32 ug/ml), S. enterica serovar Typhimurium MS4252S (phoPQ mutant defensin supersusceptible) (MIC 2
Evidence 8 Activity

Activity

MIC
Antiparasitic
32 µg/mL

Target

Staphylococcus epidermidis clinical isolate

Source & Reference

NA

Other

t (MIC 16-32 ug/ml), Gram+ S. aureus NCTC 4163 or MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/m
Evidence 9 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

NA

Other

r MRSA R147 (MIC 32-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 32 ug/ml), E. faecalis ATCC 29212 (MIC 64 ug/ml), and yeast . C. albicans 105 or 3153A (MIC 64 ug/ml or greater) ( PubMed ).