Back to search

Peptide record

TPDB11119

Antibacterial Antifungal Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11119
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIMDTIKNAAKDVVQSLLNKASCKLAKTC
Physicochemical Analysis
C130H231N37O41S3
REHFPWY
K
3064.67
9.65
5
2
12
+3
5.83
0.086
101.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.08
9
Residue Composition
number
4
A
0
R
2
N
2
D
2
C
0
E
1
Q
1
G
0
H
2
I
3
L
5
K
1
M
0
F
0
P
2
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 3 K: 5 M: 1 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
29
C130H231N37O41S3
3064.67
9.65
+3
5.83
0.086
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S.aureus ATCC 25923, E.faecalis 981 (inactive), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 2 Activity

Activity

MIC
Antibacterial
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

01118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922 (MIC 150 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (inactive). Updated 5/2019 7/20
Evidence 3 Activity

Activity

MIC
Antifungal
2.3 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S.aureus ATCC 25923, E.faecalis 981 (inactive), N. asteroides 201118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922
Evidence 4 Activity

Activity

MIC
Antifungal
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

01118 (MIC 2.3 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), E.coli ATCC 25922 (MIC 150 uM), C.albicans ATCC 10231 (inactive), and C.glabrata 090902 (inactive). Updated 5/2019 7/20
Evidence 5 Activity

Activity

19.5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
19.5% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 6 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017