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Peptide record

TPDB11113

Antibacterial Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11113
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
AQWFAIQHISLNPPRSTIAMRAINNYRWR
Physicochemical Analysis
C159H244N50O39S1
DCEGKV
ARI
3512.06
12.40
5
0
14
+4
-0.56
-0.469
81.03
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
12490
355.63
9
Residue Composition
number
4
A
4
R
3
N
0
D
0
C
0
E
2
Q
0
G
1
H
4
I
1
L
0
K
1
M
1
F
2
P
2
S
1
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 4 N: 3 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 1 I: 4 L: 1 K: 0 M: 1 F: 1 P: 2 S: 2 T: 1 W: 2 Y: 1 V: 0
Chemical Descriptors
29
C159H244N50O39S1
3512.06
12.40
+4
-0.56
-0.469
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
10.3±0.1 µM
Hemolytic Cytotoxic
50% Hemolysis | 10.3±0.1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Refining the eosinophil cationic protein antibacterial pharmacophore by rational structure minimization. | J Med Chem | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis