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Peptide record

TPDB11109

Antibacterial Antifungal Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11109
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFCIPIRCPGHTRQIGTCFGPRVKSCRKW
Physicochemical Analysis
C145H231N47O34S4
ANDELMY
RCG
3304.96
10.57
7
0
7
+6
2.63
-0.300
50.34
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5750
173.98
8
Residue Composition
number
0
A
4
R
0
N
0
D
4
C
0
E
1
Q
4
G
1
H
3
I
0
L
2
K
0
M
2
F
3
P
1
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 4 E: 0 Q: 1 G: 4 H: 1 I: 3 L: 0 K: 2 M: 0 F: 2 P: 3 S: 1 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
29
C145H231N47O34S4
3304.96
10.57
+6
2.63
-0.300
Evidence Records 3 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
<10% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Artificial beta-defensin based on a minimal defensin template. | Biochem J | 2009
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Artificial beta-defensin based on a minimal defensin template. | Biochem J | 2009
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis