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Peptide record

TPDB11101

Antibacterial Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11101
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GALRRLGRKITHAVKKYGPTVLRIIRIAG
Physicochemical Analysis
C145H257N49O33
NDCEQMFSW
R
3214.94
12.59
9
0
13
+8
4.52
-0.003
124.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
46.35
3
Residue Composition
number
3
A
5
R
0
N
0
D
0
C
0
E
0
Q
4
G
1
H
4
I
3
L
3
K
0
M
0
F
1
P
0
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 4 L: 3 K: 3 M: 0 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
29
C145H257N49O33
3214.94
12.59
+8
4.52
-0.003
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
18.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 18.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Analogues of peptide SMAP-29 with comparable antimicrobial potency and reduced cytotoxicity. | Int J Antimicrob Agents | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
1.63 µM
Cytotoxic
50% Cell death | 1.63 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Analogues of peptide SMAP-29 with comparable antimicrobial potency and reduced cytotoxicity. | Int J Antimicrob Agents | 2011
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis