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Peptide record

TPDB11083

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB11083
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GLMDTVKNAAKNLAGQMLDKLKCKITGSC
Physicochemical Analysis
C128H227N37O40S4
REHFPWY
K
3052.67
9.65
5
2
11
+3
5.34
-0.079
87.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.09
8
Residue Composition
number
3
A
0
R
2
N
2
D
2
C
0
E
1
Q
3
G
0
H
1
I
4
L
5
K
2
M
0
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 4 K: 5 M: 2 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
29
C128H227N37O40S4
3052.67
9.65
+3
5.34
-0.079
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
90 µM
Hemolytic Cytotoxic
50% Hemolysis | 90 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Primary structures of skin antimicrobial peptides indicate a close, but not conspecific, phylogenetic relationship between the leopard frogs Lithobates onca and Lithobates yavapaiensis (Ranidae). | Comp Biochem Physiol C Toxicol Pharmacol | 2010
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.