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Peptide record

TPDB11063

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11063
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GLGSLLGKAFKFGLKTVGKMMGGAPREE
Physicochemical Analysis
C129H215N35O35S2
NDCQHIWY
G
2880.46
10.55
5
2
11
+3
4.37
-0.021
73.21
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
2
E
0
Q
7
G
0
H
0
I
4
L
4
K
2
M
2
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 7 H: 0 I: 0 L: 4 K: 4 M: 2 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
28
C129H215N35O35S2
2880.46
10.55
+3
4.37
-0.021
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 2 Activity

Activity

MIC
Antibacterial
6 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 3 Activity

Activity

MIC
Antifungal
6 µM

Target

Escherichia coli

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 4 Activity

Activity

MIC
Antifungal
6 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP Antifungipept

Other

Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 5 Activity

Activity

MIC
Antiparasitic
6 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 6 Activity

Activity

MIC
Antiparasitic
6 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 6 uM) and S. aureus (MIC 6 uM), Hemolytic HL50 =105 uM.
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
105 µM
Hemolytic Cytotoxic
50% Hemolysis | 105 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific. | Peptides | 2011
Evidence 8 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.