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Peptide record

TPDB11060

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11060
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIMDSVKNAAKNLAGQLLDTIKCKITAC
Physicochemical Analysis
C124H219N35O39S3
REHFPWY
AK
2920.49
9.05
4
2
12
+2
4.34
0.254
108.21
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.28
8
Residue Composition
number
4
A
0
R
2
N
2
D
2
C
0
E
1
Q
2
G
0
H
3
I
3
L
4
K
1
M
0
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 2 D: 2 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 3 L: 3 K: 4 M: 1 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
28
C124H219N35O39S3
2920.49
9.05
+2
4.34
0.254
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Upd
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Updated 12/2023
Evidence 3 Activity

Activity

MIC
Antifungal
25 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Upd
Evidence 4 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Updated 12/2023
Evidence 5 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Upd
Evidence 6 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

S.aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Updated 12/2023
Evidence 7 Activity

Activity

MIC
Antiviral
25 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Upd
Evidence 8 Activity

Activity

MIC
Antiviral
>150 µM

Target

S.aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 25 uM) but not S.aureus (MIC>150 uM). Warning: Activity was tested with 2PLa in this series. Updated 12/2023