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Peptide record

TPDB11054

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11054
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AVPpred-BWR APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
IKIPAVVKDTLKKVAKGVLSAVAGALTQ
Physicochemical Analysis
C129H232N34O35
RNCEHMFWY
AKV
2819.47
10.71
5
1
15
+4
4.84
0.689
139.29
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
0
R
0
N
1
D
0
C
0
E
1
Q
2
G
0
H
2
I
3
L
5
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 3 K: 5 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 5
Chemical Descriptors
28
C129H232N34O35
2819.47
10.71
+4
4.84
0.689
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
20-40 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 3 Activity

Activity

MIC
Antiparasitic
20-40 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 4 Activity

Activity

MIC
Antiviral
20-40 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20-40 uM).
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
>300 µM
Hemolytic Cytotoxic
50% Hemolysis | >300 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The hymenochirins: a family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae). | Peptides | 2012
Evidence 6 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.