Back to search

Peptide record

TPDB11050

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11050
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GILDTIKNAAKTVAVGLLEKIKCKMTGC
Physicochemical Analysis
C127H228N34O37S3
RQHFPSWY
K
2919.59
9.65
5
2
12
+3
5.38
0.439
115.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.28
6
Residue Composition
number
3
A
0
R
1
N
1
D
2
C
1
E
0
Q
3
G
0
H
3
I
3
L
5
K
1
M
0
F
0
P
0
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 1 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 3 K: 5 M: 1 F: 0 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
28
C127H228N34O37S3
2919.59
9.65
+3
5.38
0.439
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
17 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
70 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
17 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
70 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
17 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
70 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 7 Activity

Activity

MIC
Antiviral
17 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 8 Activity

Activity

MIC
Antiviral
70 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 17 uM) and S. aureus (MIC 70 uM), but not C.albicans (very weakly MIC 150 uM).
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptides and protease inhibitors in the skin secretions of the crawfish frog, Rana areolata. | Biochim Biophys Acta | 2002
Evidence 10 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.