TPDB11044

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 0.5-2 µM

Target

Target Organism Escherichia coli ATCC 25922 ML-35 or D21

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism S. typhimurium ATCC 14028

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism Pseudomonas aeruginosa ATCC 27853

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

nst E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2 µM

Target

Target Organism S. marcescens ATCC 8100

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM),

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1-4 µM

Target

Target Organism Staphylococcus aureus ATCC 25923 or Cowan 1 MRSA

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

4028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism Staphylococcus epidermidis ATCC 12228

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Ant

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism B. megaterium Bm11

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited ba

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. malto

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 4 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. maltophilia (0.5 MIC) nhibited bac

Evidence 10 Activity

Activity

Activity Raw

Not Available

Detail Source Activity Anticancer

Target

Cancer Type Not Available

Cell Line Not Available

Tissue Affected Not Available

Assay & Model

Assay Not Available

Testing Time Not Available

Source & Reference

Database Source dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb

Source CancerPPD2

Year 1996

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 0.5-2 µM

Target

Target Organism Escherichia coli ATCC 25922 ML-35 or D21

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1 µM

Target

Target Organism S. typhimurium ATCC 14028

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1 µM

Target

Target Organism Pseudomonas aeruginosa ATCC 27853

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

nst E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2 µM

Target

Target Organism S. marcescens ATCC 8100

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM),

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1-4 µM

Target

Target Organism Staphylococcus aureus ATCC 25923 or Cowan 1 MRSA

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

4028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1 µM

Target

Target Organism Staphylococcus epidermidis ATCC 12228

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Ant

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1 µM

Target

Target Organism B. megaterium Bm11

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited ba

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 8 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. malto

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 4 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

ermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. maltophilia (0.5 MIC) nhibited bac

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 0.5-2 µM

Target

Target Organism Escherichia coli ATCC 25922 ML-35 or D21

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1 µM

Target

Target Organism S. typhimurium ATCC 14028

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1 µM

Target

Target Organism Pseudomonas aeruginosa ATCC 27853

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

nst E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2 µM

Target

Target Organism S. marcescens ATCC 8100

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM),

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1-4 µM

Target

Target Organism Staphylococcus aureus ATCC 25923 or Cowan 1 MRSA

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

4028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1 µM

Target

Target Organism Staphylococcus epidermidis ATCC 12228

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Ant

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1 µM

Target

Target Organism B. megaterium Bm11

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited ba

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 8 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. malto

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 4 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. maltophilia (0.5 MIC) nhibited bac

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 0.5-2 µM

Target

Target Organism Escherichia coli ATCC 25922 ML-35 or D21

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label	Source Definition
Antiviral	DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1 µM

Target

Target Organism S. typhimurium ATCC 14028

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

Active against E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1 µM

Target

Target Organism Pseudomonas aeruginosa ATCC 27853

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

nst E. coli ATCC 25922 ML-35 or D21 (MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2 µM

Target

Target Organism S. marcescens ATCC 8100

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

MIC 0.5-2 uM), S. typhimurium ATCC 14028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM),

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1-4 µM

Target

Target Organism Staphylococcus aureus ATCC 25923 or Cowan 1 MRSA

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

4028 (MIC 1 uM), P. aeruginosa ATCC 27853 (MIC 1 uM), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1 µM

Target

Target Organism Staphylococcus epidermidis ATCC 12228

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

), S. marcescens ATCC 8100 (MIC 2 uM), S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Ant

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 1 µM

Target

Target Organism B. megaterium Bm11

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

S. aureus ATCC 25923 or Cowan 1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited ba

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 8 µM

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

1 MRSA (MIC 1-4 uM), S. epidermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. malto

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 4 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source dbAMP 3.0 DRAMP DRAVP 2.0

Other

Evidence Text

ermidis ATCC 12228 (MIC 1 uM), B. megaterium Bm11 (MIC 1 uM), C. albicans (MIC 8 uM), and C. neoformans (MIC 4 uM). Antibiofilm:bacteria: inhibited bacterial biofilm:S. maltophilia (0.5 MIC) nhibited bac

Evidence 38 Activity

Activity

Activity Endpoint 15% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 3 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

15% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. | J Biol Chem | 1996

Evidence 39 Activity

Activity

Activity Endpoint 90% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 100 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

90% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. | J Biol Chem | 1996

Evidence 40 Activity

Activity

Activity Endpoint 60% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 20 µM

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

60% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Structure-function study of cathelicidin-derived bovine antimicrobial peptide BMAP-28: design of its cell-selective analogs by amino acid substitutions in the heptad repeat sequences. | Biochim Biophys Acta | 2009

Evidence 41 Activity

Activity

Activity Endpoint 50% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 60 µg/mL

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

50% Hemolysis | 60 | µg/mL | target cell: Bovine erythrocytes

Target

Target Cell Bovine erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Stability, Toxicity, and Biological Activity of Host Defense Peptide BMAP28 and Its Inversed and Retro-Inversed Isomers | Biopolymers | 2011

Evidence 42 Activity

Activity

Activity Endpoint 50% Cell death

Detail Source Activity Toxicity

Activity Measurement 15 µg/mL

Toxicity Type Cytotoxic

Toxicity Raw

50% Cell death | 15 | µg/mL | target cell: Bovine intestinal epithelial cells

Target

Target Cell Bovine intestinal epithelial cells

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Stability, Toxicity, and Biological Activity of Host Defense Peptide BMAP28 and Its Inversed and Retro-Inversed Isomers | Biopolymers | 2011

Evidence 43 Hemolysis

Source & Reference

source APD_complete APD_hemolytic HemoPI PD_Hemolysis

Database Source APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label	Source Definition
Hemolysis	APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.