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Peptide record

TPDB11043

Antibacterial Antifungal Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11043
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLADYWRTAFRANFANLGPGIRCKSARC
Physicochemical Analysis
C137H212N44O36S2
EQHMV
A
3115.58
10.41
5
1
12
+4
-0.76
-0.257
59.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7115
228.37
7
Residue Composition
number
5
A
4
R
2
N
1
D
2
C
0
E
0
Q
3
G
0
H
1
I
2
L
1
K
0
M
2
F
1
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 4 N: 2 D: 1 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 2 P: 1 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
28
C137H212N44O36S2
3115.58
10.41
+4
-0.76
-0.257
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>64 µM
Hemolytic Cytotoxic
50% Hemolysis | >64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and functional characterization of novel antimicrobial peptides from the skin of brown frog, Rana zhenhaiensis. | Zoolog Sci | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis