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Peptide record

TPDB11034

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11034
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RVIEVVQGACRAIRHIPRRIRQGLERIL
Physicochemical Analysis
C143H255N53O35S1
NDKMFSTWY
R
3308.99
12.28
8
2
12
+5
9.26
-0.082
135.71
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
7
R
0
N
0
D
1
C
2
E
2
Q
2
G
1
H
5
I
2
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 7 N: 0 D: 0 C: 1 E: 2 Q: 2 G: 2 H: 1 I: 5 L: 2 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
28
C143H255N53O35S1
3308.99
12.28
+5
9.26
-0.082
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
5% Hemolysis | 16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization | J Antimicrob Chemother | 1999
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human cystic fibrosis airway epithelial cells

Target

Human cystic fibrosis airway epithelial cells

Source & Reference

NA
DBAASP
Selective toxicity of engineered lentivirus lytic peptides in a CF airway cell model. | Peptides | 2003