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Peptide record

TPDB11031

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11031
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GLMDTIKGVAKNVAASLLEKLKCKVTGC
Physicochemical Analysis
C125H224N34O37S3
RQHFPWY
K
2891.54
9.65
5
2
12
+3
5.50
0.400
111.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.32
6
Residue Composition
number
3
A
0
R
1
N
1
D
2
C
1
E
0
Q
3
G
0
H
1
I
4
L
5
K
1
M
0
F
0
P
1
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 1 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 5 M: 1 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
28
C125H224N34O37S3
2891.54
9.65
+3
5.50
0.400
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Escherichia coli ATCC 25726

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus A
Evidence 2 Activity

Activity

MIC
Antibacterial
80 µM

Target

Klebsiella pneumoniae ATCC 700603

Source & Reference

dbAMP

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans
Evidence 3 Activity

Activity

MIC
Antibacterial
20 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
80 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

(MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
40 µM

Target

Candida albicans ATCC 90028

Source & Reference

dbAMP

Other

(MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
20 µM

Target

Escherichia coli ATCC 25726

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus A
Evidence 7 Activity

Activity

MIC
Antifungal
80 µM

Target

Klebsiella pneumoniae ATCC 700603

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans
Evidence 8 Activity

Activity

MIC
Antifungal
20 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
80 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
40 µM

Target

Candida albicans ATCC 90028

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Escherichia coli ATCC 25726

Source & Reference

NA

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus A
Evidence 12 Activity

Activity

MIC
Antiparasitic
80 µM

Target

Klebsiella pneumoniae ATCC 700603

Source & Reference

NA

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans
Evidence 13 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

Active against E. coli ATCC 25726 (MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 14 Activity

Activity

MIC
Antiparasitic
80 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

(MIC 20 uM), K. pneumoniae ATCC 700603 (MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
40 µM

Target

Candida albicans ATCC 90028

Source & Reference

NA

Other

(MIC 80 uM), P. aeruginosa ATCC 27853 (MIC 20 uM), S. aureus ATCC 25923 (MIC 80 uM), and C. albicans ATCC 90028 (MIC 40 uM).
Evidence 16 Activity

Activity

50% Hemolysis
Toxicity
120 µM
Hemolytic Cytotoxic
50% Hemolysis | 120 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona. | Peptides | 2011
Evidence 17 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.