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Peptide record

TPDB11015

Antibacterial Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB11015
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AKLWLKAAKLWLKAAKLWLKAAKLWLKA
Physicochemical Analysis
C164H266N40O29
RNDCEQGHIMFPSTYV
ALK
3262.17
11.36
8
0
20
+8
-5.32
0.357
140.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
22000
674.40
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
8
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 8 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
28
C164H266N40O29
3262.17
11.36
+8
-5.32
0.357
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1 µM
Hemolytic Cytotoxic
5% Hemolysis | 1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric ?-helical peptides with Gly-Gly pairs. | Sci Rep | 2015