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Peptide record

TPDB10986

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB10986
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
IKIPAFVKDTLKKVAKGVISAVAGALTQ
Physicochemical Analysis
C133H232N34O35
RNCEHMWY
AK
2867.51
10.71
5
1
15
+4
3.89
0.664
128.93
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
5
A
0
R
0
N
1
D
0
C
0
E
1
Q
2
G
0
H
3
I
2
L
5
K
0
M
1
F
1
P
1
S
2
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 3 L: 2 K: 5 M: 0 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 4
Chemical Descriptors
28
C133H232N34O35
2867.51
10.71
+4
3.89
0.664
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
20 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20 uM).
Evidence 3 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20 uM).
Evidence 4 Activity

Activity

MIC
Antiviral
20 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

st Gram-negative bacteria such as E. coli, P. Aeruginosa, K. pneumoniae and Gram-positive S. aureus (MIC 20 uM).
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
160 µM
Hemolytic Cytotoxic
50% Hemolysis | 160 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The hymenochirins: a family of host-defense peptides from the Congo dwarf clawed frog Hymenochirus boettgeri (Pipidae). | Peptides | 2012
Evidence 6 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.