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Peptide record

TPDB10978

Antibacterial Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10978
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRRRRRRRRGGGKWKKLLKKPLKLLKK
Physicochemical Analysis
C154H287N63O28
ANDCEQHIMFSTYV
R
3469.38
13.31
17
0
6
+17
11.04
-2.089
72.22
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
158.53
0
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
5
L
8
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 5 K: 8 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
27
C154H287N63O28
3469.38
13.31
+17
11.04
-2.089
Evidence Records 1 records
Evidence 1 Activity

Activity

6.7% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
6.7% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Conjugation of Cell-Penetrating Peptides to Antimicrobial Peptides Enhances Antibacterial Activity. | ACS Omega | 2019