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Peptide record

TPDB10966

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10966
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGTKFLGGVKTALKGALKELASTYVN
Physicochemical Analysis
C125H210N32O36
RDCQHMPW
G
2737.24
10.31
4
1
12
+3
2.01
0.278
104.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
54.43
6
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
1
E
0
Q
5
G
0
H
1
I
4
L
4
K
0
M
1
F
0
P
1
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 0 I: 1 L: 4 K: 4 M: 0 F: 1 P: 0 S: 1 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
27
C125H210N32O36
2737.24
10.31
+3
2.01
0.278
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtili
Evidence 2 Activity

Activity

MIC
Antibacterial
4.7 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
9.4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

clude Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtili
Evidence 6 Activity

Activity

MIC
Antifungal
4.7 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
9.4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

clude Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

NA

Other

peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtili
Evidence 10 Activity

Activity

MIC
Antiparasitic
4.7 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiparasitic
9.4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

clude Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiparasitic
75 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiviral
75 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

NA

Other

peptides (i.e. AMPs) with MIC < 100 ug/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtili
Evidence 14 Activity

Activity

MIC
Antiviral
4.7 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

/ml are registered. Microbes tested include Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 15 Activity

Activity

MIC
Antiviral
9.4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

clude Fungus C. albicans ATCC 20032 (MIC 75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 16 Activity

Activity

MIC
Antiviral
75 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

75 ug/ml), S. aureus ATCC 25923 (MIC 4.7 ug/ml), E. coli ATCC 25922 (MIC 9.4 ug/ml), and B. subtilis ATCC 6633 (MIC 75 ug/ml).
Evidence 17 Activity

Activity

28% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
28% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 18 Activity

Activity

16% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
16% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 19 Activity

Activity

12% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 20 Activity

Activity

2% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 21 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.