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Peptide record

TPDB10965

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10965
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGTKFLGGVKTALKGALKELAFTYVN
Physicochemical Analysis
C131H214N32O35
RDCQHMPSW
G
2797.33
10.31
4
1
13
+3
0.75
0.411
104.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
53.27
5
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
1
E
0
Q
5
G
0
H
1
I
4
L
4
K
0
M
2
F
0
P
0
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 0 I: 1 L: 4 K: 4 M: 0 F: 2 P: 0 S: 0 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
27
C131H214N32O35
2797.33
10.31
+3
0.75
0.411
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP

Other

0 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 8 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

0 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

0 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E. coli ATCC 25922 (MIC 37.5 ug/ml), and B.subtilis ATCC 6633 (MIC>100 ug/ml).
Evidence 13 Activity

Activity

4% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 14 Activity

Activity

2% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 15 Activity

Activity

0% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 16 Activity

Activity

0% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011