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Peptide record

TPDB10964

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10964
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGGVLLSAGKAALKGLTKVLAEKYAN
Physicochemical Analysis
C120H208N32O34
RDCQHMFPW
AGL
2643.17
10.31
4
1
14
+3
1.96
0.500
126.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
56.37
4
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
1
E
0
Q
5
G
0
H
1
I
5
L
4
K
0
M
0
F
0
P
1
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 0 I: 1 L: 5 K: 4 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
27
C120H208N32O34
2643.17
10.31
+3
1.96
0.500
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 8 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 13 Activity

Activity

9% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
9% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 14 Activity

Activity

3% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 15 Activity

Activity

1% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 16 Activity

Activity

1% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011