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Peptide record

TPDB10963

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10963
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGGVLLGAGKATLKGLAKVLAEKYAN
Physicochemical Analysis
C119H206N32O33
RDCQHMFPSW
G
2613.14
10.31
4
1
14
+3
1.84
0.515
126.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
57.02
3
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
1
E
0
Q
6
G
0
H
1
I
5
L
4
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 6 H: 0 I: 1 L: 5 K: 4 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
27
C119H206N32O33
2613.14
10.31
+3
1.84
0.515
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 8 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
18.8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

E.coli ATCC 25922

Source & Reference

NA

Other

y active peptides (i.e. AMPs) with MIC 100 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

B.subtilis ATCC 6633

Source & Reference

NA

Other

00 ug/ml), S. aureus ATCC 25923 (MIC 18.8 ug/ml), E.coli ATCC 25922 (MIC >100 ug/ml), and B.subtilis ATCC 6633 (MIC >100 ug/ml).
Evidence 13 Activity

Activity

24% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
24% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 14 Activity

Activity

4% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 15 Activity

Activity

11% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
11% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 16 Activity

Activity

1% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 17 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.