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Peptide record

TPDB10960

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10960
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGGALLSVGKLALKGLANVLADKFAN
Physicochemical Analysis
C119H204N32O33
RCEQHMPTWY
L
2611.12
10.32
3
1
15
+2
-0.29
0.833
141.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
5
A
0
R
2
N
1
D
0
C
0
E
0
Q
5
G
0
H
1
I
6
L
3
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 1 L: 6 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
27
C119H204N32O33
2611.12
10.32
+2
-0.29
0.833
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 37.5 ug/ml).
Evidence 2 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 37.5 ug/ml).
Evidence 3 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 37.5 ug/ml).
Evidence 4 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

NA

Other

Proteomics: Only active peptides (i.e. AMPs) with MIC 100 ug/ml), and B. subtilis ATCC 6633 (MIC 37.5 ug/ml).
Evidence 5 Activity

Activity

41% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
41% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 6 Activity

Activity

18% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 7 Activity

Activity

28% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
28% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 8 Activity

Activity

17% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
17% Hemolysis | 62.5 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
There are abundant antimicrobial peptides in brains of two kinds of Bombina toads. | J Proteome Res | 2011
Evidence 9 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.