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Peptide record

TPDB10952

Antibacterial Anticancer Antifungal Antiparasitic standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10952
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ALSILRGLEKLAKMGIALTNCKATKKC
Physicochemical Analysis
C125H228N36O34S3
DQHFPWYV
LK
2875.59
10.39
6
1
12
+5
3.82
0.300
115.93
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
4.35
6
Residue Composition
number
4
A
1
R
1
N
0
D
2
C
1
E
0
Q
2
G
0
H
2
I
5
L
5
K
1
M
0
F
0
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 2 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 5 K: 5 M: 1 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C125H228N36O34S3
2875.59
10.39
+5
3.82
0.300
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
28 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activit
Evidence 2 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP0
Evidence 3 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP00617. Need further validatio
Evidence 4 Activity

Activity

MIC
Antifungal
28 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activit
Evidence 5 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP0
Evidence 6 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP00617. Need further validatio
Evidence 7 Activity

Activity

MIC
Antiparasitic
28 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activit
Evidence 8 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

S.aureus

Source & Reference

DRAMP

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP0
Evidence 9 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

C.albicans

Source & Reference

DRAMP

Other

Active against E. coli (MIC 28 uM) but not S.aureus (MIC>150 uM) and C.albicans (MIC>150 uM). Warning: Antibacterial activity was tested together with AP00617. Need further validatio