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Peptide record

TPDB10951

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10951
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0 ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLPRKILCAIAKKKGKCKGPLKLVCKC
Physicochemical Analysis
C129H238N38O28S4
NDEQHMFSTWY
K
2897.79
10.53
9
0
9
+9
5.57
0.070
104.81
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
250
8.63
4
Residue Composition
number
2
A
1
R
0
N
0
D
4
C
0
E
0
Q
3
G
0
H
2
I
4
L
8
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 4 K: 8 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
27
C129H238N38O28S4
2897.79
10.53
+9
5.57
0.070
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.4 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
8.6 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
15 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
3.6 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

ve against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
0.4 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
8.6 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
15 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
3.6 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ve against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 9 Activity

Activity

MIC
Antiparasitic
0.4 µM

Target

B. subtilis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 10 Activity

Activity

MIC
Antiparasitic
8.6 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
15 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
3.6 µM

Target

Candida albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

ve against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 13 Activity

Activity

MIC
Antiviral
0.4 µM

Target

B. subtilis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 14 Activity

Activity

MIC
Antiviral
8.6 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 15 Activity

Activity

MIC
Antiviral
15 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 16 Activity

Activity

MIC
Antiviral
3.6 µM

Target

Candida albicans

Source & Reference

dbAMP 3.0 DRAMP

Other

ve against B. subtilis (MIC 0.4 uM), E. coli (MIC 8.6 uM), P. aeruginosa (MIC 15 uM), and C. albicans (MIC 3.6 uM).
Evidence 17 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lasiocepsin, a novel cyclic antimicrobial peptide from the venom of eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). | Amino Acids | 2012
Evidence 18 Activity

Activity

LC50
Toxicity
200 µM
Hemolytic
Hemolytic_activity: [Ref.22038181]LC50>200 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2012 Aug 43(2):751-761.