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Peptide record

TPDB10925

Antibacterial Antifungal Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10925
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept APD_complete PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFFHIIKGLFHAGRMIHGLVNRRRHRH
Physicochemical Analysis
C155H238N54O29S1
DCEQPSTWY
RH
3354.00
13.00
11
0
12
+6
3.39
-0.256
86.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
5
R
1
N
0
D
0
C
0
E
0
Q
3
G
5
H
3
I
2
L
1
K
1
M
4
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 5 I: 3 L: 2 K: 1 M: 1 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
27
C155H238N54O29S1
3354.00
13.00
+6
3.39
-0.256
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as
Evidence 2 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as MICs. UPdated 7/2021 6
Evidence 3 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

V. parahaemolyticus

Source & Reference

NA

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as MICs. UPdated 7/2021 6/2025
Evidence 4 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as
Evidence 5 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as MICs. UPdated 7/2021 6
Evidence 6 Activity

Activity

MIC
Antifungal
2.5 µM

Target

V. parahaemolyticus

Source & Reference

Antifungipept

Other

Active against E. coli (MIC 2.5 uM), S. aureus (MIC 2.5 uM), and V. parahaemolyticus (MIC 2.5 uM). MBC values are the same as MICs. UPdated 7/2021 6/2025
Evidence 7 Activity

Activity

19% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
19% Hemolysis | 20 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Two isoforms of piscidin from Malabar grouper, Epinephelus malabaricus: Expression and functional characterization. | Fish Shellfish Immunol | 2016
Evidence 8 Activity

Activity

75% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
75% Hemolysis | 20 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Two isoforms of piscidin from Malabar grouper, Epinephelus malabaricus: Expression and functional characterization. | Fish Shellfish Immunol | 2016
Evidence 9 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.