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Peptide record

TPDB10914

Antibacterial Antifungal Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10914
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GIGGALLSAGKAALKGLAKGLAEHFAN
Physicochemical Analysis
C114H191N33O32
RDCQMPTWYV
A
2535.97
10.32
4
1
14
+2
1.13
0.511
112.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
1
E
0
Q
6
G
1
H
1
I
5
L
3
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 6 H: 1 I: 1 L: 5 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C114H191N33O32
2535.97
10.32
+2
1.13
0.511
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
100% Hemolysis | 80 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Feleucin-BO1: A Novel Antimicrobial Non-Apeptide Amide from the Skin Secretion of the Toad, Bombina orientalis, and Design of a Potent Broad-Spectrum Synthetic Analogue, Feleucin-K3. | Chem Biol Drug Des | 2015