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Peptide record

TPDB10909

Antibacterial Anticancer Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10909
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GEILCNLCTGLINTLENLLTTKRKRQQ
Physicochemical Analysis
C130H230N40O41S2
ADHMFPSWYV
L
3073.62
9.11
4
2
8
+2
6.18
-0.300
115.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.07
11
Residue Composition
number
0
A
2
R
3
N
0
D
2
C
2
E
2
Q
2
G
0
H
2
I
6
L
2
K
0
M
0
F
0
P
0
S
4
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 3 D: 0 C: 2 E: 2 Q: 2 G: 2 H: 0 I: 2 L: 6 K: 2 M: 0 F: 0 P: 0 S: 0 T: 4 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C130H230N40O41S2
3073.62
9.11
+2
6.18
-0.300
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
50% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis=10 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Proc Natl Acad Sci U S A. 1994 Mar 29 91(7):2602-6.
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis