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Peptide record

TPDB10900

Antibacterial Antiparasitic Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB10900
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and dbAMP 3.0, with an available 3D structural model.
Sequence
GNGNLLGGLLRPVLGVVKGLTGGLGKK
Physicochemical Analysis
C116H207N35O31
ADCEQHIMFSWY
G
2588.14
11.73
4
0
10
+4
1.59
0.374
133.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
0
E
0
Q
9
G
0
H
0
I
7
L
3
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 9 H: 0 I: 0 L: 7 K: 3 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
27
C116H207N35O31
2588.14
11.73
+4
1.59
0.374
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli. | Gene | 2017
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli. | Gene | 2017
Evidence 3 Activity

Activity

85% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
85% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagonian frog Pleurodema thaul (Anura: Leptodactylidae: Leiuperinae) with activity against Escherichia coli. | Gene | 2017